Picture a strawberry. Most people can easily distinguish between the image in their mind's eye and a real strawberry. Researchers have now identified how the brain makes this distinction and pinpointed the key region where this process occurs.

According to a recent study published in Science Advances, the primary visual cortex plays a crucial role in distinguishing between visual memories and real-time visual inputs. This area of the brain, typically associated with processing visual information, shows distinct neuronal activity patterns for recalled images compared to those seen in real life.

Lead researcher Dajun Xing from Beijing Normal University conducted experiments with macaque monkeys, using microelectrode arrays implanted in their primary visual cortex. The study demonstrated that when monkeys recalled specific images, such as colors or shapes, the neuronal activity patterns differed significantly from when they were viewing these stimuli directly.

"This study provides compelling evidence that the primary visual cortex is involved in visual memory," says cognitive neuroscientist Floris de Lange from Radboud University. However, some experts, like Julio Martinez-Trujillo from Western University, suggest that the prefrontal cortex may also play a critical role in visual memory.

Further research is needed to fully understand how different brain regions contribute to the formation and retrieval of visual memories. Future studies could involve manipulating brain activity to observe its effect on memory recall, shedding more light on this fascinating aspect of cognitive neuroscience.

For more details on this groundbreaking study, read the full article in Science Advances.

More: https://www.nature.com/articles/d41586-024-01757-3