The article, "Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins", was published in Neuron in May 2017. The retraction notice, issued February 11, 2025 states: "We, the authors of this publication, have decided to retract the paper because we found that the images in Figure 1D and Figure S4B contain aberrations that cannot be explained, and the original data for these figures are missing. Raw data for the other components of the paper are available, and their reanalysis confirmed the conclusions of the paper. We would like to thank M. Schrag for bringing these image aberrations to our attention."

The retraction is the second for Südhof. Several corrections on his papers have also been issued recently, Science reported in May 2024, with many other papers flagged on PubPeer. A regularly updated page on Südhof’s website details the concerns and actions taken to investigate. He is one of 22 Nobel Prize winners who have had papers retracted.

Another high-profile case has interested scientists. Read now